Lessons from two prevalent amyloidoses—what amylin and Aβ have in common
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چکیده
منابع مشابه
Lessons from two prevalent amyloidoses—what amylin and Aβ have in common
The amyloidogenic peptide Aβ plays a key role in Alzheimer's disease (AD) forming insoluble aggregates in the brain. The peptide shares its amyloidogenic properties with amylin that forms aggregates in the pancreas of patients with Type 2 Diabetes mellitus (T2DM). While epidemiological studies establish a link between these two diseases, it is becoming increasingly clear that they also share bi...
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ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2013
ISSN: 1663-4365
DOI: 10.3389/fnagi.2013.00038